Sunday, May 5, 2013

Boston bomb suspect died of gunshots, blunt trauma

In this Feb. 17, 2010, photo, Tamerlan Tsarnaev, left, accepts the trophy for winning the 2010 New England Golden Gloves Championship from Dr. Joseph Downes, right, in Lowell, Mass. Tsarnaev, 26, who had been known to the FBI as Suspect No. 1 in the Boston Marathon Explosions and was seen in surveillance footage in a black baseball cap, was killed overnight on Friday, April 19, 2013, officials said. (AP Photo/The Lowell Sun, Julia Malakie) MANDATORY CREDIT;

In this Feb. 17, 2010, photo, Tamerlan Tsarnaev, left, accepts the trophy for winning the 2010 New England Golden Gloves Championship from Dr. Joseph Downes, right, in Lowell, Mass. Tsarnaev, 26, who had been known to the FBI as Suspect No. 1 in the Boston Marathon Explosions and was seen in surveillance footage in a black baseball cap, was killed overnight on Friday, April 19, 2013, officials said. (AP Photo/The Lowell Sun, Julia Malakie) MANDATORY CREDIT;

Peter Stefan, funeral director and owner of Graham, Putnam and Mahoney Funeral Parlors in Worcester, Mass., sits in one of the facility's rooms Friday, May 3, 2013. Stefan confirmed his funeral home will handle funeral arrangements for Boston Marathon bombing suspect Tamerlan Tsarnaev, but did not say whether he had possession of the body. (AP Photo/The Telegram & Gazette, Chris Christo)

Police cars sit across from the Graham, Putnam and Mahoney Funeral Parlors, in Worcester, Mass., Friday, May 3, 2013. Owner Peter Stefan confirmed his facility will handle funeral arrangements for Boston Marathon bombing suspect Tamerlan Tsarnaev, but did not say whether he had possession of the body. (AP Photo/The Telegram & Gazette)

Map locates Boston funeral home associated with Boston Marathon bombing.

Massachusetts State Police walk out of the woods of The Smith Neck Farm in Dartmouth, Mass. on Friday, May 3, 2013 as federal, state and local authorities on Friday searched the woods near the UMass-Dartmouth campus as part of the marathon investigation. (AP Photo/The Standard-Times, John Sladewski)

(AP) ? A suspect in the Boston Marathon bombings died from gunshot wounds and blunt trauma to his head and torso, a funeral director said Friday.

Worcester funeral home owner Peter Stefan has 26-year-old Tamerlan Tsarnaev's body and read details from his death certificate. The certificate cites Tsarnaev's "gunshot wounds of torso and extremities" and lists the time of his death as 1:35 a.m. on April 19, four days after the deadly bombing, Stefan said.

Tsarnaev died after a gunfight with authorities who had launched a massive manhunt for him and his brother, ethnic Chechens from Russia who came to the United States about a decade ago. Police have said he ran out of ammunition before his younger brother dragged his body under a vehicle while fleeing.

Tsarnaev's family on Friday was making arrangements for his funeral as investigators searched the woods near a college attended by 19-year-old Dzhokhar Tsarnaev, who was captured less than a day after his brother's death.

The funeral parlor in Worcester is familiar with Muslim services and said it will handle arrangements for Tamerlan Tsarnaev, whose body was released by the state medical examiner Thursday.

The body initially was taken to a North Attleborough funeral home, where it was greeted by about 20 protesters. Stefan, owner of Graham Putnam and Mahoney Funeral Parlors in Worcester, an hour's drive west of Boston, said everybody deserves a dignified burial service no matter the circumstances of his or her death and he is prepared for protests.

"My problem here is trying to find a gravesite. A lot of people don't want to do it. They don't want to be involved with this," said Stefan, who said dozens of protesters gathered outside his funeral home, upset with his decision to handle the funeral. "I keep bringing up the point of Lee Harvey Oswald, Timothy McVeigh or Ted Bundy. Somebody had to do those, too."

Meanwhile, two U.S. officials said Dzhokhar Tsarnaev told interrogators that he and his brother initially considered setting off their bombs on July Fourth.

Boston police said they planned to review security procedures for the Independence Day Boston Pops concert and fireworks display, which draws a crowd of more than 500,000 annually and is broadcast to a national TV audience. Authorities plan to look at security procedures for large events held in other cities, notably the massive New Year's Eve celebration held each year in New York City's Times Square, Massachusetts state police spokesman David Procopio said.

Gov. Deval Patrick said everything possible will be done to assure a safe event.

"I think the most important thing is that we got them, and there's investigation continuing about where the other leads may lead," he said. "I can tell you, having been thoroughly briefed, that the law enforcement at every level is pursuing everything."

As part of the bombing investigation, federal, state and local authorities were searching the woods near the University of Massachusetts Dartmouth campus, where Dzhokhar Tsarnaev was a student. Christina DiIorio-Sterling, a spokeswoman for U.S. Attorney Carmen Ortiz, could not say what investigators were looking for but said residents should know there is no threat to public safety.

Dzhokhar Tsarnaev, who was found hiding in a tarp-covered boat in a suburban Boston backyard, faces a charge of using a weapon of mass destruction to kill. Three of his college classmates were arrested Wednesday and accused of helping after the bombing to remove a laptop and backpack from his dormitory room before the FBI searched it.

The April 15 bombing, using pressure cookers packed with explosives, nails, ball bearings and metal shards, killed three people and injured more than 260 others near the marathon's finish line.

The brothers decided to carry out the attack before Independence Day when they finished assembling the bombs, the surviving suspect told interrogators after he was arrested, according to two U.S. officials briefed on the investigation. The officials spoke on condition of anonymity because they were not authorized to discuss the ongoing investigation.

Investigators believe some of the explosives used in the attack were assembled in Tamerlan Tsarnaev's home, though there may have been some assembly elsewhere, one of the officials said. It does not appear that the brothers ever had big, definitive plans, the official said.

The brothers' mother insists the allegations against them are lies.

Meanwhile, the Department of Homeland Security ordered border agents to immediately begin verifying that every international student who arrives in the U.S. has a valid student visa, according to an internal memorandum obtained Friday by The Associated Press. The new procedure is the government's first security change directly related to the Boston bombings.

The order from a senior official at U.S. Customs and Border Protection, David J. Murphy, was circulated Thursday and came one day after President Barack Obama's administration acknowledged that one of the students accused of hiding evidence, Azamat Tazhayakov, of Kazakhstan, was allowed to return to the U.S. in January without a valid student visa.

Tazhayakov's lawyer has said he had nothing to do with the bombing and was shocked by it.

A benefit concert featuring Aerosmith, James Taylor and Jimmy Buffett is scheduled for May 30 at the TD Garden in Boston. The proceeds will go to The One Fund, which has taken in more than $28 million for those injured and the families of those who were killed.

The fund's administrator, Kenneth Feinberg, said Friday he plans to hold meetings with victims next week and begin cutting checks by the end of June.

___

Associated Press writers Bridget Murphy and Mark Pratt in Boston and Pete Yost, Eileen Sullivan and Alicia A. Caldwell in Washington contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-05-03-US-Boston-Marathon-Explosions/id-cd0bf9b08bfe4f0686567d34ae696f57

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Saturday, May 4, 2013

Washington Post profit plunges 85 percent on weak news, education revenues

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/washington-post-profit-plunges-85-percent-weak-news-131543426.html

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More love for Jennifer Lawrence in less makeup

Celebs

25 minutes ago

Jennifer Lawrence has already impressed us by winning an Oscar and by being fun pretty much every time she shows up anywhere. The actress caught our attention again this week by putting her freshest face forward at the New York premiere of "The Great Gatsby" on Wednesday.

Image: Jennifer Lawrence

Startracksphoto.com, Getty Images

Jennifer Lawrence at the premiere of "The Great Gatsby" in New York on May 1, left, and at the GLAAD Media Awards in Los Angeles on April 20.

At 22 years old it certainly wouldn't take much for Lawrence to pull off a youthful glow. But her minimal-makeup look was striking enough to make headlines, perhaps because we've become so accustomed to the super smokey eyes she and many of Hollywood's leading ladies stare back at us with these days.

It's not like she was snapped by the paparazzi while running out for a quadruple Americano in her sweat pants. Those makeup-free photos always seem to make us happy that stars do wear makeup. This was a major film premiere at New York's Lincoln Center. Leonardo DiCaprio was there. And other spiffy people.

Wearing a sleeveless black dress with her hair pulled back and no jewelry, the star of "Silver Linings Playbook" and "The Hunger Games" was almost unrecognizable for all the right reasons -- her natural beauty and her lack of fear of showing her "real" face in public.

Source: http://www.today.com/entertainment/jennifer-lawrence-wears-less-makeup-we-fall-even-more-love-6C9756585

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Syrian opposition blames regime for village deaths

BEIRUT (AP) ? Syria's main opposition group on Friday accused President Bashar Assad's regime of committing a "large-scale massacre" in a Sunni village near the Mediterranean coast the previous day, leaving at least 50 people dead, according to activists.

The Britain-based Syrian Observatory for Human Rights said Syrian troops backed by pro-government gunmen swept into Bayda, a village in the mountains outside the city of Banias on Thursday, killing people, including women and children, and torching homes.

The group documented the names of at least 50 dead but says as many as 100 may have been killed. The Observatory, which relies on a network of activists on the ground, cited witnesses as saying that some of the victims were killed with knives or blunt objects and that dozens of villagers were still missing.

"Reports now confirm a large-scale massacre in Bayda," the Syrian National Coalition said in a statement. "Initial reports confirm that Assad's forces were directly involved" in the violence in the area, the statement added. The Coalition urged the international community to act and protect Syrian civilians.

"It is time for the world to intervene and put an end to the grievous crimes of the Assad regime," the Cairo-based opposition group said in a statement emailed to the media Friday.

The Syrian troops were still in Bayda village on Friday, conducting house to house searches, said Rami Abdul Rahman, the Observatory's director. He added that phones in the area remained cut off and communication with witnesses was only possible through satellite telephones.

The Syrian conflict, now in its third year, started as peaceful protests against Assad's rule in March 2011. It turned into armed conflict between the opposition and the government after some opposition supporters took up weapons to fight a harsh regime crackdown on dissent and soon became a full-scale civil war.

More than 70,000 people have been killed so far in the conflict, according to the United Nations. Over a million Syrians have fled their homes and sought shelter in neighboring countries such as Jordan, Lebanon and Turkey, while millions more have been internally displaces by the fighting.

The war has also split the country along religious lines, and the violence in Bayda appeared to have sectarian overtones. The village is primarily inhabited by Sunni Muslims, who dominate the country's rebel movement, while most of the surrounding villages are home to members of President Bashar Assad's Alawite sect, an offshoot of Shiite Islam.

If confirmed, the violence in Bayda would be the latest in a string of alleged mass killings in Syria's civil war. Last month, activists said government troops killed more than 100 people as they seized two rebel-held suburbs of Damascus.

The relentless fighting has left the international community at a loss to find ways to end the bloodshed as neither side appears willing to find a political solution at the moment.

While the U.S. and its European and Gulf allies have backed the opposition forces, they have been reluctant to provide the rebels fighting Assad's troops with weapons that could stand up to the regime's superior firepower. They fear the arms could end up in the hands of radical Islamic groups that in the past year have become the most effective fighting force on the opposition's side.

On Thursday, President Barack Obama said his administration is looking at every option to end the bloodshed in Syria. Speaking during a news conference in Mexico City, Obama said the administration is proceeding cautiously as it looks at options, to ensure that what it does is helpful to the situation rather than making it more deadly or complex.

In Washington, Obama's defense secretary, Chuck Hagel, became the first top U.S. official to acknowledge publicly that the administration is rethinking its opposition to arming the Syrian rebels.

During a Pentagon news conference Thursday, Hagel said that "arming the rebels ? that's an option," but added that the administration was looking at all options. "It doesn't mean that the president has decided on anything," Hagel said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-05-03-Syria/id-4ebd3194398a48a7adb7cf2f450d0720

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Friday, May 3, 2013

Jolla names Tomi Pienim?ki as new CEO, Marc Dillon to become Head of Software Development

Jolla names Tomi Pienimki as new CEO, Marc Dillon to become Head of Software Development

As Jolla gears up for the imminent unveiling of its first smartphone packing the MeeGo-inspired Sailfish OS, there's been another shake-up at the highest level of the company. Marc Dillion will no longer be CEO as of May 6th, with a man by the name of Tomi Pienimäki taking over leadership of the company. He's no stranger to Jolla -- he's an investor and his brother Sami is one of the company's founders. Using nearly the same wording as when previous CEO Jussi Hurmola changed roles, Dillon will now be able to "fully concentrate on the development of Sailfish operating system" under his new title of Head of Software Development. Pienimäki's record shows he's all business, with experience in management, logistics, supply chains and driving growth -- you know, all the fun stuff that keeps a company ticking. Following the handset reveal in May, Jolla expects to start a "pre-sales campaign" in the same month and have devices available for purchase during the second half of this year.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/2Bn-LLpclaI/

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Newcastle Historical Society patriarch turns 95 : Newcastle News ...

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Home / Local News / Newcastle Historical Society patriarch turns 95

May 2, 2013

By Christina Corrales-Toy

By Christina Corrales-Toy Newcastle historian Milt Swanson cuts into a piece of carrot cake at a celebration of his 95th birthday during the Newcastle Historical Society's April 4 meeting at City Hall.

By Christina Corrales-Toy
Newcastle historian Milt Swanson cuts into a piece of carrot cake at a celebration of his 95th birthday during the Newcastle Historical Society?s April 4 meeting at City Hall.

No one knows more about the history of Newcastle than Milt Swanson.

That?s because he lived it. He watched as the trains weaved in and out through the city; he worked in the mines as his father and grandfather did before him; and he understands how the coal mining industry shaped the city into what it is today.

When Swanson talks at the monthly Newcastle Historical Society meetings, people listen as he tells stories about what it was like to grow up in Old Newcastle.

?His vivid memory just makes the history come alive for the people that hear him speak,? said Pam Lee, Newcastle Historical Society member.

The group dedicated to preserving Newcastle?s history celebrated its most valuable member at its April 4 meeting, with a birthday party in Swanson?s honor.

Born March 29, 1918, in the area now occupied by the Coal Creek Family YMCA, Swanson said he distinctly remembers hearing the whistle of the trains as they traveled through town toward Seattle.

?I must?ve been only 3 or 4 years old and I vividly remember standing behind the picket fence, looking through it and seeing the steam engines running up and down on the railroad tracks,? he said.

Swanson has spent all of his 95 years living in the same area, 90 of which were in the same company house that still stands at the edge of town near the Cougar Mountain trailhead.

?Like I like to say, I couldn?t find any place better,? he said. ?I?ve done quite a bit of traveling and I never found any place I?ve liked better than this.?

At 95 years old, Swanson said he doesn?t get around as easily as he used to.

?It really feels like 95 sometimes,? he joked.

The Newcastle historian is still as sharp as they come, Lee said, and his ability to remember minute details of his life and the history of the city is a marvel to Newcastle Historical Society members.

?Whether it?s about his boyhood or his great-grandmother being at the cemetery, his story is Newcastle?s story,? Lee said. ?It just seems so real, and I think that?s pretty special.?

Written by Christina Corrales-Toy ? Filed Under Local News?

Copyright 2010 by Issaquah Press Inc. All rights reserved. This material may not be published, rewritten or redistributed without permission. E-mail editor@isspress.com

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Source: http://www.newcastle-news.com/2013/05/02/newcastle-historical-society-patriarch-turns-95

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Identifying inhibitors of human proteins that promote tumor formation

Identifying inhibitors of human proteins that promote tumor formation [ Back to EurekAlert! ] Public release date: 3-May-2013
[ | E-mail | Share Share ]

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, May 2, 2013Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer. A novel, high-throughput screening method used to identify agents that can block one chemical modifier that plays a key role in some forms of cancer is described in ASSAY and Drug Development Technologies, a peer-reviewed journal published from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available on the ASSAY and Drug Development Technologies website (http://www.liebertpub.com/adt).

Jeffrey Simard, Matthew Plant, Renee Emkey, and Violeta Yu, Amgen, Inc. (Cambridge, MA) present an optimized, robust assay for screening large numbers of chemical compounds against EZH2 methyltransferase. This enzyme is part of a multi-protein complex which can alter the methylation state of chromosomal proteins. Increased EZH2 methyltransferase activity has been associated with reduced expression of tumor repressor genes.

In the article "Development and Implementation of a High-Throughput AlphaLISA Assay for Identifying Inhibitors of EZH2 Methyltransferase" (http://online.liebertpub.com/doi/full/10.1089/adt.2012.481) the authors describe the use of AlphaLisa technology to detect methylation by EZH2 and emphasize that this approach should accelerate the identification of small molecule inhibitors for use as research tools and for development as novel anti-cancer therapeutics.

###

About the Journal

Assay and Drug Development Technologies is an authoritative peer-reviewed journal published 10 times a year in print and online. It provides early-stage screening techniques and tools that enable identification and optimization of novel targets and lead compounds for new drug development. Complete tables of content and a complementary sample issue may be viewed on the ASSAY and Drug Development Technologies website ((http://www.liebertpub.com/adt).

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including OMICS: A Journal of Integrative Biology and Genetic Testing and Molecular Biomarkers. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website (http://www.liebertpub.com).

Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101
http://www.liebertpub.com


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Identifying inhibitors of human proteins that promote tumor formation [ Back to EurekAlert! ] Public release date: 3-May-2013
[ | E-mail | Share Share ]

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, May 2, 2013Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer. A novel, high-throughput screening method used to identify agents that can block one chemical modifier that plays a key role in some forms of cancer is described in ASSAY and Drug Development Technologies, a peer-reviewed journal published from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available on the ASSAY and Drug Development Technologies website (http://www.liebertpub.com/adt).

Jeffrey Simard, Matthew Plant, Renee Emkey, and Violeta Yu, Amgen, Inc. (Cambridge, MA) present an optimized, robust assay for screening large numbers of chemical compounds against EZH2 methyltransferase. This enzyme is part of a multi-protein complex which can alter the methylation state of chromosomal proteins. Increased EZH2 methyltransferase activity has been associated with reduced expression of tumor repressor genes.

In the article "Development and Implementation of a High-Throughput AlphaLISA Assay for Identifying Inhibitors of EZH2 Methyltransferase" (http://online.liebertpub.com/doi/full/10.1089/adt.2012.481) the authors describe the use of AlphaLisa technology to detect methylation by EZH2 and emphasize that this approach should accelerate the identification of small molecule inhibitors for use as research tools and for development as novel anti-cancer therapeutics.

###

About the Journal

Assay and Drug Development Technologies is an authoritative peer-reviewed journal published 10 times a year in print and online. It provides early-stage screening techniques and tools that enable identification and optimization of novel targets and lead compounds for new drug development. Complete tables of content and a complementary sample issue may be viewed on the ASSAY and Drug Development Technologies website ((http://www.liebertpub.com/adt).

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including OMICS: A Journal of Integrative Biology and Genetic Testing and Molecular Biomarkers. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website (http://www.liebertpub.com).

Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101
http://www.liebertpub.com


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/mali-iio050313.php

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